Welcome to the Stone Research Group at the University of California, Santa Cruz. |
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Michael D. Stone, Ph.D. - principal investigator Department of Chemistry and Biochemistry Center for Molecular Biology of RNA
The Stone Research Group combines the use of biochemical techniques with newly emerging single-molecule biophysical methods to probe enzyme structure and dynamics of protein-nucleic acid interactions.
Our current area of focus is the structure and function of the telomerase ribonucleoprotein, an RNA-dependent DNA polymerase that maintains genomic stability by synthesizing repetitive DNA sequences at chromosome termini. These short DNA repeats form the foundation of specialized chromatin structures, called telomeres, that prevent deleterious chromosome fusion events by differentiating chromosome ends from sites of DNA damage.(more) |
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News:Nov. 10, 2009. Kevin Najarro was awarded the UCSC Crown College Undergraduate Research Fellowship! Sept. 1, 2009. John Loper is now the full time SRG lab technician/manager. June 17, 2009. The SRG welcomes Ben Akiyama (MCD Biology Graduate Student) to the lab! We congratulate Ben on being chosen by the Graduate Advising Committee to receive a National Institutes of Health graduate trainee award funded by our MCD Biology NIH training grant. May 15, 2009. The SRG has been awarded a Special Research Grant from the UCSC Committee on Research to support a collaborative project with Bill Scott's group which aims to use single molecule techniques to study hammerhead ribozyme structure and function. Location:The Stone Research Group is located in the Physical Sciences Building, amidst the beautiful redwood trees on the UC Santa Cruz campus. 
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